Welcome to Breathe Equal

Sanofi wants to see a world where everyone can #BreatheEqual. To #BreatheEqual is to imagine a world without inequalities in respiratory care and outcomes.

Mission Statement

Sanofi has created the #BreatheEqual campaign which shines a light on the inequalities that exist in respiratory care and demonstrates how we are working to prioritise these issues amongst patients, government, industry and the NHS. Our ambition is to see improvements in the recognition, diagnosis and quality of care for those suffering with respiratory conditions, regardless of location and socio-economic status.

The #BreatheEqual campaign has brought together clinical and patient advocacy voices to discuss the issues with the current respiratory pathway and explore what potential alternative models can be created to better improve care across the UK. Through collaboration with stakeholders from across respiratory health, we hope to provide recommendations for clinicians and policymakers that will improve the lives of patients for the long term.

Background on Asthma

It is estimated that around 1 million people in the UK have ‘difficult’ asthma and around 200,000 people in the UK have ‘severe’ asthma.1

People with severe asthma have persistent symptoms that don’t respond to conventional, high dose preventative treatment2 and may experience frequent life-threatening asthma attacks and regular hospital admissions.3

The UK has one of the worst mortality rates for asthma in Europe.4 For those living with the most severe forms of asthma, underdiagnosis and delayed referral to specialists are contributing to these poor outcomes.5

Deprivation is associated with higher rates of mortality from asthma in England – in 2020 the most deprived groups had mortality rates that were more than triple those of the least deprived.6

Evidence also shows that asthma patients experience inequalities in outcomes on the basis of their gender,7 race,8 and socioeconomic status.9

Background on COPD

Chronic Obstructive Pulmonary Disease (COPD) is a group of lung conditions that cause difficulty breathing due to obstruction or narrowing of the airways.

It is the fifth most common cause of death in the United Kingdom and causes a significant number of hospitalisations, accounting for 133,103 emergency hospital admissions in England in 2019/2010, making it the second leading cause of emergency admissions.11

As with asthma, there is significant geographic variation in the prevalence of COPD – prevalence of COPD in the 10% most deprived areas of England is estimated to be double that of the most affluent 10%.12

Policy Asks

To deliver meaningful change that bridges the gaps in equitable access, diagnosis and treatment; addresses the gender disparity of hospitalisation and mortality rates for women; and ensures ethnic minority groups are no longer more likely to be admitted to hospital for respiratory conditions; we recommend the following policy changes:

  • A review of existing guidelines, pathways and policies to ensure factors associated with variation in respiratory treatment and outcomes are addressed proactively (including, where appropriate, co-creation with affected groups) 
  • The NHS must commit to exploring all available therapies in instances of treatment failure and to end the prescribing of maintenance oral corticosteroids (OCS) as a default treatment.
  • A coordinated, national approach to joining up respiratory data from across the health system, with all tiers of NHS provision required to input into a new platform.

Read more about these policy asks in the ‘Our Respiratory Mission’ section below.

The #BreatheEqual Challenges

Our Respiratory Mission

References

1 Asthma UK (2018), Slipping through the net: the reality facing patients with difficult and severe asthma. Available from: https://www.asthma.org.uk/support-us/campaigns/publications/difficult-and-severe-asthma-report/  (Last accessed in April 2024)

2 BMJ (opinion) (2018) Andy Whittamore: People with severe asthma are slipping through the net. Available at https://blogs.bmj.com/bmj/2018/09/07/andy-whittamore-people-with-severe-asthma-are-slipping-through-the-net/ (Last accessed in April 2024)

3 Asthma UK (2018) Slipping through the net https://www.asthma.org.uk/support-us/campaigns/publications/difficult-and-severe-asthma-report/ (Last accessed in April 2024)

4 Asthma UK UK asthma death rates among worst in Europe. Available at: https://www.asthma.org.uk/about/media/news/press-release-uk-asthma-death-rates-among-worst-in-europe/

5 Royal College of Physicians (2015). Why asthma still kills: National Review of Asthma Deaths. Available from: https://www.rcplondon.ac.uk/projects/outputs/why-asthma-still-kills

6 UK Government (2021). Interactive Health Atlas of Lung conditions in England (INHALE): November 2021 update. Available from: https://www.gov.uk/government/statistics/interactive-health-atlas-of-lung-conditions-in-england-inhale-november-2021-update/interactive-health-atlas-of-lung-conditions-in-england-inhale-november-2021-update

7 ALUK. Women almost twice as likely to die from asthma than men. Data from: Office for National Statistics (ONS) – England & Wales, Northern Ireland Statistics & Research Agency (NISRA), National Records of Scotland (NR Scotland). 2022. Available at https://www.asthmaandlung.org.uk/women-almost-twice-as-likely-to-die-from-asthma-than-men/ [Accessed on 8th June 2022]

8 Busby J et al. UK Severe Asthma Registry. Ethnic Differences in Severe Asthma Clinical Care and Outcomes: An Analysis of United Kingdom Primary and Specialist Care. J Allergy Clin Immunol Pract. 2022;10(2):495-505.

9 Alsallakh MA, Rodgers SE, Lyons RA, Sheikh A, Davies GA. Association of socioeconomic deprivation with asthma care, outcomes, and deaths in Wales: A 5-year national linked primary and secondary care cohort study. PLoS medicine. 2021;18(2).

10 Office for Health Improvement and Disparities. Public health profiles - COPD [Internet]. Fingertips Public Health Profiles. Available from: https://fingertips.phe.org.uk/search/COPD

11 NICE. Chronic obstructive pulmonary disease in over 16s: diagnosis and management (update) (NG115). 2018 Dec.

12 Kulakiewicz A, Baker C, Macdonald M. Support for people with chronic obstructive pulmonary disease [Internet]. 2021. Available from: https://commonslibrary.parliament.uk/research-briefings/cdp-2021-0188/

MAT-XU-2304563 (v1.0)

June 2024